I'm not saying that there Is no link between Synthroid and lung cancer. Link posted. "Serum TSH, T(4), and thyroid antibodies in the United States population (1988 to 1994): National Health and Nutrition Examination Survey (NHANES III)". Furthermore, the geometric expansion of hypothyroidism cases in the past decade only thinly conceals an agenda to promote the synthetic form of T4 known as levothyroxine sodium (trade name Synthroid), since with each new 'disease' case the patient is converted into a lifelong customer. Oops I have just bought my first jar of marmalade in over ten years! [7] They also elaborate on a mechanism of T4-induced lung tissue toxicity: "[I]n rats lung the deiodination of LT4 is the lowest compared to all the other tissues. hyperthyroidism. [6] Venditti P, Di Stefano L, Di Meo S: Oxidative stress in cold induced hyperthyroid state. Assessment of oxidative stress and its balance has not been taken into consideration up to now as it should be.". Thyroid disease is a major public health concern worldwide. Non-small cell lung cancer is the most common type of lung cancer, accounting for about 81% of all cases. Symptoms can include fatigue, shortness of breath with exercise, and decreased ability to exercise. May be of interest: Study: Millions Treated for Hypothyroidism At Risk for, Non-small cell lung cancer - Adenocarcinoma, Non-small cell lung cancer - Squamous cell, Top 5 Questions to Ask Your Lung Cancer Doctor, Patient & Caregiver Network Member Resources, Not A Member Yet? In 2020 alone, there were more than 2.2 million new cases and 1.8 million deaths from lung cancer globally. However, that information will still be included in details such as numbers of replies. Or, if fluoride, mercury, or any number of xenobiotic chemicals in the environment requiring selenium-dependent glutathione-mediated detoxification is causing the low thyroid, why call chemical poisoning hypothyroidism? New Cholesterol Drug Guaranteed to Prematurely Kil Beware the Walgreens travel vaccination scam. Metab.87 (2): 48999. I don't believe there are thousands of people on to high a dose of t4, so why does it feel they are hyper? It is very tormenting (for me anyhow) to not know why I got this disease. Other research indicating that increased thyroid activity (hyperthyroidism) contributes to lung cancer pathogenesis was presented, including: The authors also cite animal experimental research which has shown that T4 increases the oxidative stress[6] and spontaneous pulmonary metastases in mice. Or that it was the many years of not being diagnosed with hypothyroidism, courtesy of daft blood test ranges, before finally tipping a TSH over 5 (or even 10) before treatment is commenced, by which time the damage is done. Correlation is NOT causation. video where the doc is talking about the study , i wlll link study and video below. If You Don't Want Older Bones, Don't Be Low In Vit Background Mortality Rate for Vaccines, or Pseudo Everything You Ever Wanted to Know About Black Seeds. I have always found this condition a riddle. Very interesting article, thank you for sharing. Desiccated thyroid extract compared with levothyroxine in the treatment of hypothyroidism: a randomized, double-blind, crossover study. The authors of the study pointed out that levothyroxine (T4) treatment can lead to medication-induced (iatrogenic) thyroid over-activity (hyperthyroidism) and oxidative stress that can lead to a significant patient discomfort. Monaldi Arch Chest Dis 2003, 59:140145. [12] Cesarone MR, Belcaro G, Nicolaides AN, Incandela L, De Sanctis MT, Barsotti A: San Valentino epidemiologic project. Privacy Policy. For a better experience, please enable JavaScript in your browser before proceeding. ", Cure Alveolar Soft Part Sarcoma International, COMPLETED - Dana Farber Vaccine Clinical Trial (GVAX), Axitinib and Pembrolizumab (Keytruda) in Miami, US, TECENTRIQ (atezolizumab) by Genentech, Treatment of Non-Resectable Primary Tumor, Immune checkpoint inhibitors ICI (PD-1 and PD-L1 targeting drugs), Toxicity, problems and potentiation strategies, Treatment response criteria and evaluation/scanning problems/rare cases, treatment discontinuation/re-treatment, Side effects/complications of the local ablations, High intensity focused ultrasound (HIFU), Study: Millions Treated for Hypothyroidism At Risk for Lung Cancer, http://www.greenmedinfo.com/blog/study- ng-cancers. Allthewebsites Directory - A niche web directory offering website promotion and other webmaster resources. ", Orsomeone posts something about, say a diet or supplement and them some people think they are something it "Cures lung cancer.". This website is for information purposes only. Overtreatment, of course, is the hallmark danger of overdiagnosis. Based just on this article, I think the study's conclusion that Synthroid may cause an increase in lung cancer risk is premature. Asesora y Consultora Web3 para empresas. I have so many women friends and family members who have recently been diagnosed with hypothyroidism and their doctors put them all on Synthyroid. She wrote about a product called Thyrtophin PMG. Currently, the best practical approach is to base treatment decisions on the degree of TSH elevation, thyroid autoimmunity, and associated comorbidities. Even acute bouts of stress and subclinical adrenal insufficiency can cause cyclical downshifts in thyroid function. Nah, I would give this much credence. PMID 11836274. The reality is that most cases of hypothyroidism today are diagnosed in populations who are experiencing a combination of basic nutritional deficiencies and chemical exposures, or who are simply going through a temporary down-cycle in thyroid function following a natural change, such as the natural postpartum drop that occurs in women after giving birth. Eventually, the decline in thyroid hormone production can result in any of the following: Fatigue and sluggishness. LifeGivingStore.comRed Light Therapy - Hydrogen Water Generators - Cascara Sagrada - Vitamins, Minerals & Amino Acid Supplements - Cocoa Products - Handcrafted Soaps - Grass Fed Organs & Glandulars - Nano Soma. [2] Meng R, Tang HY, Westfall J, London D, Cao JH, Mousa SA, Luidens M, Hercbergs A, Davis FB, Davis PJ, et al: Crosstalk between integrin v3 and estrogen receptor- is involved in thyroid hormone-induced proliferation in human lung carcinoma cells. Symptoms. Indeed, research indicates that hypothyroid patients treated with T4 replacement, that is sufficient to maintain a normal serum TSH, actually have serum free T4 that is higher than in untreated normal patients and may not result in appropriately normal serum free T3 concentrations. I have so much to say about this I could write a book. Finally, they pointed out that T4, which is a synthetic form of thyroid hormone, might be avoided if T3 or the desiccated pig-derived form known as Armour Thyroid was used to control the oxidative-stress producing hydroperoxides. It took over five years before the someone figured out my ongoing symptoms were due to hypothyroidism. [14] In other words, you can normalize the main clinically measurable parameter associated with low thyroid function, i.e. Just another excuse for keeping us on doses that are too low. [10] Hofer T, Desbaillets I, Hpfl G, Wenger RH, Gassmann M: Characterization of HIFD-1 alpha overexpressing Hela cells and implication for gene therapy. Ultimately, this latest Italian study is bringing to our attention one of what is likely a wide range of unintended, adverse health effects associated with the overdiagnosis and subsequent overtreatment of hypothyroidism, and the underlying failure of the conventional, largely drug-based paradigm to comprehend the causes and real solutions of disease and human suffering. elevated TSH, without actually improving the overall physiological situation, nor the patient's subjective experience of well being. J Endocrinol Invest. Biomedicine today is awash in controversy associated with the overdiagnosis and overtreatment of asymptomatic populations. Curr Opin Endocrinol Diabetes Obes 2010, 17:432436. Heart problems. Are you sure you want to block this member? PMID: 15253676. People read a study and think that someone like, perhaps me, is saying "it Causes lung cancer. As a person with Graves Disease, I underwent 6 cycles of radio-ablation using i 131 to 'fry' my thyroid gland as surgery was deemed too risky due to the vascularity and size of my gland. Ultimately, this Italian study brings further attention to one of a wide range of unintended, adverse health effects associated with the overdiagnosis and subsequent overtreatment of hypothyroidism, and the underlying failure of the conventional, largely drug-based paradigm to comprehend the causes and real solutions of disease and human suffering. [7] Kinoshita S, Sone S, Yamashita T, Tsubura E, Ogura T: Effects of experimental hyperand hypothyroidism on natural defense activities against Lewis lung carcinoma and its spontaneous pulmonary metastases in C57BL/6 mice. [9] Otto T, Fandrey J: Thyroid hormone induces hypoxia-inducible factor 1 gene expression through thyroid hormone receptor /retinoid x receptor -dependent activation of hepatic leukemia factor. The very concept of "marketing" is at odds with the real nature of these materials, which has to do with the protection and expansion of our nature and potential. Cookie Notice There are many links attached. Overtreatment, of course, is the hallmark danger of overdiagnosis. I have posted the link, so you can see if it has any merit. So I will leave it as a simple thank you for passing this along. 16.6k members in the AlternativeHealth community. A distorted idea of human nature is sold when people are treated as "the market. The aim of the study was to assess the occurrence and nature of immune-related endocrine adverse events (irAEs) among patients with non-small-cell lung cancer (NSCLC) treated with nivolumab. The study looked at the prevalence of breast, colorectal, gastric and lung cancer in 18 Italian Regions during 2010 and correlated this data with sales of LT4 in 2009, focusing on women aged 30-84. The authors expanded on their findings further: However, the impression we get from our experience in epidemiological studies monitoring[12] is that this drug should be prescribed more cautiously. Levothyroxine therapy and serum free thyroxine and free triiodothyronine concentrations. Just go on one of the thyroid sites and read the stories. An Italian study published in the journalReproductive Biology and Endocrinology,titled Levothyroxine and lung cancer in females: the importance of oxidative stress, has raised a concerning possibility: levothyroxine (T4), one of the worlds most commonly prescribed forms of hormone replacement, may be raising the risk of lung cancer in millions of men and women being treated for low thyroid function (hypothyroidism). The omnipresent environmental contaminant perchlorate, an ingredient in jet fuel, is also a primary cause of hypothyroidism, but is almost never tested for by the conventional endocrinologists in their patient evaluations. Capmatinib (Tabrecta) is the first FDA-approved MET-targeting medication for treating metastatic NSCLC. The Flu Propaganda Matrix Continues To Promote Fea B Vitamins Slow Alzheimer's and Grey Matter Loss. Biomedicine today is awash in controversy associated with the overdiagnosis and overtreatment of asymptomatic populations. [9] [10] [11] Although we should never forget that LT4 is a life-saving thyroid hormone replacement, and that one should not exclude that the pathological reason that leads to the prescription of LT4 could favor the lung cancer development also. ', Study: Millions Treated for Hypothyroidism At Risk for Lung Cancer. I honestly do not know. I have no further scientific evidence. Si as lo deseas puedes revisar el resto de nuestros contenidos para encontrar lo que buscabas o directamente utilizar nuestro buscador. They found no significant correlation between T4 sales and breast, colorectal and gastric cancers, but did find a significant correlation for lung cancer (p < 0.05) corrected for smoking and age. If I can help someone, fine. [4] Ratcliffe JG, Stack BH, Burt RW, Radcliffe WA, Spilg WG, Cuthbert J, Kennedy RS: Thyroid function in lung cancer. The Goji Berry: The Jolly Super Food That Gives Yo How to Prevent and Treat Insect Bites Without Hars Supreme Court Rules Drug Companies Exempt From Law Spain Study Confirms Hemp Oil Cures Cancer without Wheatgrass Turns Gray Hair Back to Its Natural Color, Medicinal Cannabis Used To Prevent Cancer Growth. Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them. Hypothyroidism can also lead to swelling of the tongue, hoarse voice, and sleep apnea. Sub-laboratory hypothyroidism and the empirical use of Armour thyroid. For more information, please see our It was the therapist that I went to that referred me to a specialist who ran the correct tests. A new study has uncovered a link between the synthetic thyroid hormone (trade name Synthroid) used to treat millions diagnosed with hypothyroidism and lung cancer, bringing to the forefront the harmful role that overdiagnosis and overtreatment plays in nutritional deficiency and chemical exposure related 'diseases.'. Indeed, research indicates that hypothyroid patients treated with T4 replacement, that is sufficient to maintain a normal serum TSH, actually have serum free T4 that is higher than in untreated normal patients and may not result in appropriately normal serum free T3 concentrations. Iodine - and the lack of it - is implicated in breast cancer, after all. The American Lung Association connects patients, families, friends and caregivers for support and inspiration as they face lung cancer. [1] Hercbergs AH, Ashur-Fabian O, Garfield D: Thyroid hormone and cancer: clinical studies of hypothyroidism in oncology. Thank you for bringing it to our attention. Is so taking anti oxidants might be an idea. [9] [10] [11] Although we should never forget that LT4 is a life-saving thyroid hormone replacement, and that one should not exclude that the pathological reason that leads to the prescription of LT4 could favor the lung cancer development also.