%PDF-1.4 Table of Contents 1. It is the responsibility of Principal Investigator (PI) to educate their staff on zoonotic diseases of the animals that they are using in their research or teaching activities. SOT Animals in Research Public Policy Statement 1999 Research involving laboratory animals is necessary to ensure and enhance human and animal health and 0000002783 00000 n A zoonotic disease is any disease that may be transmitted from an animal to a human under natural conditions. Laboratory Animals. 0000000927 00000 n Fowl Plague (OIE Reference Laboratory for Avian Influenza; FAO Reference Centre for influenza in animals and Newcastle disease) Infection with Bonamia exitiosa (NRLs for Mollusc Diseases) Infection with Bonamia ostreae (NRLs for Mollusc Diseases) The prevention or minimization of animal pain, distress, or discomfort by the proper use of tranquilizers, anesthetics, and analgesics is scientifically and ethically essential to the humane care, use, and treatment of research animals. Note: If the amount of blood volume removed is 7.5% of total blood volume, allow 1 week recovery; if amount removed is 10%, allow 2 weeks recovery; if amount removed is 15%, allow 4 weeks recovery. �y�%�$^�M���A�B���]*�L�;G����v���)`�셗"��s��82��5�Y�XGVP�I?8��zZ�yY9n�e���71�7U;��W-�Cm�Fmʳvm��(�{0�Xi�� �;~]|>g�*>)���O�_�O��ԋDf�4PY 1ka��ڏ�{RXB�&�ta�-k�蓶�Cȹ �!l�n*��=U? endobj Training 3. endobj One of the most common health risks in the research animal setting is allergic reaction to lab animals. 1. of . Read chapter DISEASES OF LABORATORY ANIMALS: Handbook of Laboratory Animals... Login Register Cart Help. Blood sample collection in small laboratory animals, J Pharmacol Pharmacother, 2010 Jul-Dec; 1(2); 87-93. 0000008218 00000 n <> Wildlife species used as research s… 0000007164 00000 n 0000001375 00000 n Introduction Laboratory animals are used for different studies It may include bioassay, preclinical studies etc. %���� 0000008239 00000 n The international journal of laboratory animal science, technology, welfare and medicine, Laboratory Animals publishes peer-reviewed original papers and reviews on all aspects of the care and use of animals in biomedical research. Animal Care and Use Committee Page . 0000004511 00000 n Animal welfare is attracting increasing interest worldwide, but particularly from those in developed countries, who now have the knowledge and resources to be able to offer the best management systems for their farm animals, as well as potentially being able to offer plentiful resources for companion, zoo and laboratory animals. 2020 2020 Volume 54 Issue 6, Current Issue December 2020 , pp. Sources of animals Under the 1986 Act the following commonly-used species that are bred for laboratory use: mouse, rat, guinea-pig, hamster, rabbit and primate must be obtained from designated breeding or supply establishments. VETERINARIANS TREATING common farm and companion species can use a wide range of drugs with regulatory approval. Laboratory/Research Skills for Science Resume List of skills to assist with resumes, cover letters and interviews Animal Care Handle and restrain Weigh animals Breed various species Clean cages Administer injections Prepare special diets Anesthetize Maintain and evaluate animal records Prepare for sterile surgical procedures Source: Adapted from Formulary for Laboratory Animals, Hawk, Leary, and Morris 2005. x��][�$�q���>Zy�+˖bgV��9��y'_���XX Q���A)����T�V�fuϬ,ـDM�R,?֍~����wq1���/����_A�xRnI�����J-�b<=���z�a��>�?_}{�o�7.0��6��P�� ����A-quޜ߾�"���_Ҫ��14IF�t�E�:����ZT���C���{H��:�3k���[�9�Ca�-��z�.��7�&��G�.ںp~��}G���:N>��^CA�:��]6W��Z��B-c:��. The 8th edition of the Guide for the Care and Use of Laboratory Animals, released in 2011, at 220 pages represented a 76% increase in information, guidance, and prescribed action from the content of the 7th edition (1996). 0000007266 00000 n A Council of Europe review of housing standards Accepted 28 October 2005 r Laboratory Animals Ltd. animals, killing animals and of those responsible for the design of procedures and projects. It is not intended to be a comprehensive text on animal anaesthesia, but concentrates on those areas that are of greatest practical importance when anaesthetizing laboratory animals. <> Monitoring 7. endobj <>stream It is estimated that anywhere from 10% to 44% of animal care workers will develop allergic symptoms to the animals. Laboratory animals are animals used for research purposes for developing and testing medicines and vaccines for humans and other animals. INTRODUCTION Selection of animal model Use of an animal phylogenetically closer to man Use of an animal in which the process under investigation is as close as possible 2. 3 0 obj 0000001735 00000 n April 1967 - December 2020 Select an issue. 0000002911 00000 n The domestic mouse, Mus musculus and related subspecies (see Mice and Rats as Laboratory Animals), is popular as a mammalian research model because of its small size, adaptability, docility, low husbandry costs, fecundity, well-defined health and genetic backgrounds, and relative ease of genetic manipulation.The development of genetic engineering techniques of inserting … 2 0 obj 525-607 Issue 5, October 2020 , pp. 0000006303 00000 n *{~��ƅ �m��:?R��n��@��8�� >�����+l�����aq?�����}��?������+�D�W��W֙�'��^~�@�,|�b�X�,���\=h�������d�C��_{�b�4�S9����E���1�[�F���� %PDF-1.2 %���� BIOLOGICAL NAMES • Genus: which have common characteristics and which can be divided into subordinate kinds. Web: www.pcrm.org <> GUIDELINES FOR ANESTHESIA AND ANALGESIA IN LABORATORY ANIMALS. laboratory animals 1. laboratory animals mehul ramanlal chorawala department of pharmacology k. b. institute of pharmaceutical education and research a constituent college of kadi sarva vishwavidyalaya gh-6, sector-23 gandhinagar-382023, gujarat 2. Animals used for laboratory research or teaching purposes at the University of Montana (UM) include mice, rats, guinea pigs, rabbits, hamsters, and birds. The paper covered the most commonly used routes in common laboratory species. Section 495 of … A report of the Institute of Laboratory Animal Resources Committee on Rat Nomenclature. Best Practices 6. 0000001951 00000 n the animal is anemic (below the normal PCV range for the species), or if the hemoglobin concentration is less than 10 g/dL, it is not safe to remove the volumes of blood listed above. The focus If you need to print pages from this book, we recommend downloading it as a PDF. • Guidelines for anesthesia and analgesia in laboratory animals; University of California. 0000002890 00000 n Study in a typical gross anatomy laboratory is based primarily on dissection of animal cadav-ers. endobj Visit NAP.edu/10766 to get more information about this book, to buy it in print, or to download it as a free PDF. techniques into the field of laboratory animal anaesthesia. <> 5 0 obj 0000001354 00000 n 0000003696 00000 n 5 Last Revised December 20, 2016. Browse by year. • Research animals must be used in a responsible manner. use in common laboratory species used in toxicity studies required by regulatory authorities; (ii) to provide consensus dosage levels for routine use that represent good practice in terms of ani-mal welfare and practicality; (iii) to produce a guide to dosage levels representing the upper limit of common practice, which leaves Healthy and well being of lab. Common Sites for Blood Collection: 0000003675 00000 n 0000009138 00000 n ), and the Animal Welfare Act (Public Law 89-544). However, there is a growing body of literature on environmental-enrichment strategies for many of the common laboratory animal species, and the Guide (NRC 1996a) provides an impetus for institutions to evaluate and incorporate enrichment measures into their animal care and use program for all species where appropriate. Collection of blood from laboratory animals is frequently necessary for a variety of experimental uses including determination of pharmacokinetics, antibody production, clinical pathology evaluation, etc. {.s���|�������-2��LPȋ���͛�ο)� Wz�,�{a���"��M�ɿ���q}���b�͞ʬ.�l7�����&���)�!z�H�tWca���"�gQj�����7< endstream endobj 69 0 obj 716 endobj 70 0 obj << /Filter /FlateDecode /Length 69 0 R >> stream E.g. animals in general) Ôbedding and nesting materials should be provided, unless it is clearly inappropriateÕ (para 3.60). OLAW and APHIS: Common Areas of Noncompliance STEPHEN POTKAY, VMD AND WILLIAM R. DEHAVEN, DVM OLAW’s Compliance Oversight: Noncompliance with PHS Policy Stephen Potkay, VMD The welfare of animals used in research has been a concern of the Public Health Service (PHS) since the mid-1900s1. This report was drawn from the scientific community from industry, academia, and animal welfare organizations. From: Lab Animal. 0000009117 00000 n The aim was to refine administration procedures and improve animal welfare and science. 6 0 obj Laboratory Animals. 0000007346 00000 n These usually have been preserved by embalming, and one or more parts of the vas-cular system have been injected with a colored material to facilitate identifi cation of the vessels. H�}T�r�0�{�����;�*���#M�qRצ]䱐A1j ��I�������������-����#JC�*US���~/��� ًC��rp� I���� �?�F�R֖���C�j1�Q[{��RT�+a2�H8��r�}1$�N� F ���0y(�VSm�&1��5�����[� }����t�1 �r�@��ۆ��:��p3Ȭ8�(����jT=��?��#�C�5��z�ޙM����4���������@-. 0000000982 00000 n 0000001597 00000 n Provides information on blood sampling techniques for many common species to help laboratory staff remove blood from animals in the most humane and efficient way. Blood may be collected from animals which are to survive the procedure or at sacrifice as a terminal event. laboratory animals according to the animal welfare and ethical norms. H�c```�k������������&J]`p����P}j��`qfE�Z��ƆY���zY\y��H�~Sq�Y��� �ޭ2SȽ(���(�����pF��R끖� �:B��ԀFa��@&�1�� (�X\@�Y���� �.I���A,"����!밆�qjc�s���x]�=�:8L xS�f2�T?��)(��ƴ�uZ�K�%�XH� ]�Hs�8L� Handling of laboratory animals and ethics 10th to 11th Novomber, 2016 Laboratory Animal Resources Section ICAR- Indian Veterinary Research Institute Izatnagar, Bareilly-243 122(U.P), India Training Program on 2000;29(5):32-37. Common laboratory animal MARTIN JACOB 1ST YR M.PHARM Department of pharmacology Shree devi college of pharmacy manglore 2. Standardized nomenclature for transgenic animals. The common education and training framework facilitates and assures the competence of all persons involved in the use, care and breeding of animals for scientific procedures, and assists the free movement of personnel. �]�h������L�X�"�/p����a����shR�L���'�&�úD�. 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