Latest news, evidence and CPD opportunities. saline IV Soln: dex/Na/K IV soln < 1 unit/mL heparin PN (NO heparin) PN (with heparin) intralipids (fats) alprostadil (PGE1) amiodarone: calcium CHLORIDE calcium GLUCONATE: How tax and accounting firms supercharge efficiency with a digital workflow, Tax pros and taxpayers take note farmers and fisherman face March 1 tax deadline, IRS provides tax relief for GA, CA and AL storm victims; filing and payment dates extended, 3 steps to achieve a successful software implementation, 2023 tax season is going more smoothly than anticipated; IRS increases number of returns processed, How small firms can be more competitive by adopting a larger firm mindset, OneSumX for Finance, Risk and Regulatory Reporting, BECRIS 2.0 How to prepare for next-level granular data reporting, Implementing Basel 3.1: Your guide to manage reforms. hb```f``9Abl,P&/ZTlb`Po&$s]/ This site complies with the HONcode standard for trust- worthy health information: verify here. Click the relevant option after each search. %%EOF Compatibility of a drug(s) is dependent on the manufacturer(s) of the products and/or the use of specific product formulations. The extent of the damage mainly depends on the patients condition (age, weight, nature, severity of the disease etc.) Visit our global site, or select a location. 194 0 obj <>stream Today hospital pharmacists have access to the entire King Guide in the pharmacy, at nurses stations, on-rounds, on-call at home, on tablets and phones - all with the same user interface and no software to install or maintain. Any other research result that does not fit the conventional guidelines of compatibility or incompatibility. IV drug compatibility in critical care Abstract: Objectives: To analyze potential (in)compatibilities of intravenous drugs based on the scheduling prepared by the nursing team. Drugs typically given by IV Many different types of medications can be given by IV. Select a second drug the same way (limited to 2 drugs) 3. (A blank space indicates no available data.) Y-Site, Syringe, and other sets/container specific information. Find out more about the antiviral medicines helping to treat COVID-19. The cost can be calculated using the average daily costof the expected clinical treatment. COMPATIBILITY Compatibility is dependent on the concentration of each medication in the total final volume being infused, rather than the actual dose. Search for and click on a drug 2. and on the type of drug administered. (2007) Preparation of a compatibility chart for intravenous drug therapy in neonatal and pediatric intensive care units. The single user license allows access from any computer or device from any location and limits access to one person at a time while the site license allows access from an unlimited number of computers or devices. Fig. Incompatibility is an undesirable reaction that occurs between the drug and the solution, container or another drug. /Feature/WoltersKluwer/OneWeb/SearchHeader/Search, The worlds most trusted medical research platform, Evidence-based drug referential solutions, Targeting infection prevention, pharmacy and sepsis management, Cloud-based tax preparation and compliance, workflow management and audit solution, Integrated tax, accounting and audit, and workflow software tools, Tax Preparation Software for Tax Preparers, Integrated regulatory compliance and reporting solution suite, Market leader in UCC filing, searches, and management, eOriginal securely digitizes the lending process from the close to the secondary market, Software solutions for risk & compliance, engineering & operations, and EHSQ & sustainability, Registered agent & business license solutions, The world's unrivalled and indispensable online resource for international arbitration research, Market-leading legal spend and matter management, contract lifecycle management, and analytics solutions, The master resource for Intellectual Property rights and registration. Morphine is frequently used for both acute pain and long-term chronic pain. Examples include: A transient precipitation formed upon mixing but then disappeared. -nF1tih$HPCQ7rGceww~@3HWw!n,GE,"? Improving clinical practice and health outcomes for Australia. About this app. Intravenous rehydration is a simple, safe and common procedure with a low risk of complications. However, published data are specific to the concentration, solvent, ambient temperature and sometimes the composition of the syringe or infusion bag. IV fluids are specially formulated liquids that are injected into a vein to prevent or treat dehydration. We streamline legal and regulatory research, analysis, and workflows to drive value to organizations, ensuring more transparent, just and safe societies. IV Drug Compatibility 12+ ITDCS Ltd Designed for iPad 1.3 16 Ratings $2.99 Screenshots iPad iPhone This application provides the healthcare profession with a method of quickly checking the compatibility of any two of the following intravenous drugs at the Y-site: Acetylcysteine Adrenaline Alfentanil Aminophylline Amiodarone Aprotinin any changes or additional incompatibilities. To view compatibility results for a list of drugs, enter multiple IV drugs and/or solutions then click "Analyze". If intravenous drugs are not mixed but are given consecutively, the infusion line should be flushed through with compatible fluid between each administration. While some general principles can be applied to the mixing of injection solutions, they are fraught with exception and applicability varies with circumstance. King Guide to Parenteral Admixtures Online Edition. within the same infusion line (simultaneous infusion) and/or IV container - administered one after the other, but within the same infusion line The salts of monovalent cations, such as sodium and potassium, are generally more soluble than those of divalent cations, such as calcium and magnesium. When a drug or solution name is in the Selected Items section, a link to the Trissels monograph for that drug/solution will be displayed. [/quote'] Aminophylline IV Push IV Push IV Push IV Push IV bolus infuse over 20 -30 minutes not to exceed 25 mg/min; max concentration 25 mg/ml. The new ASHP Injectable Drug Information now delivers the same quality of information you expect from ASHP, but expanded to deliver more information you . Fig. Bethesda: American Society of Health-System Pharmacists; 2007. Klin Padiatr; 219(1): 37-43, 7 Gikic M, Di Paolo ER, Pannatier A, Cotting J. A cost evaluation of the risk can be done by assigning costs to their related clinical treatment and resulting extended length of stay. Jonathan Petersen. For a drug molecule which acts as a proton acceptor (a Lowry-Bronsted base), ionisation is achieved by formulation in a low pH solution usually as a hydrochloride or hydrogen sulfate salt (for example, amiodarone hydrochloride or adrenaline acid tartrate). This information is not intended as a substitute for medical advice and should not be exclusively relied on to manage or diagnose a medical condition. 7db. When this occurred, "incompatible" was used. .1-.15mg/kg repeat q15 mins : Max .3mg/kg or 50mg . Available as a single . Table 3 shows the results. Over 600 IV drugs with at-a-glance view of compatibility in 12 fluids. Enabling tax and accounting professionals and businesses of all sizes drive productivity, navigate change, and deliver better outcomes. The majority of sources cited define compatibility by physical compatibility rather than chemical compatibility This table is a guide only. Visit the B. Braun product catalog with our complete portfolio. AN\=l93 eJ .Dv;wahf*|7Qq''BCLr_D]psG1W0 Adrenaline. Copyright 2022 - King Guide Publications, Inc. - All rights reserved. Intensive Care Med; 38(6):1 008-16, 14 Gianino MM, Vallino A, Minniti D, Abbona F, Mineccia C, Silvaplana P and Zotti CM. To have the most complete information possible ASHP recommends multiple sources of IV drug information be available to hospital pharmacy. The compatibility or incompatibility of IV medication is an important consideration in drug administration, especially since it is not unusual for multiple drugs to be administered through y-site connectors on continuous infusion administration sets. If drugs are mixed together, the mixture should be inspected for precipitates, turbidity or changes in colour, however not all incompatibilities are visible. Prescription and OTC drugs (over 100,000 drug products), 900+ nutraceuticals, including herbal medicines, Presented in prescriptive, immediately actionable bullet points for busy clinicians and students. No change in visible or electronically determined particulates, haziness or turbidity, frank precipitation, color, or evolution of a gas. Morphine: A narcotic pain reliever, morphine is used to reduce moderate to severe pain. Handbook on injectable drugs. 2 RCN (2010) Royal College of Nursing. Incompatibility between two intravenous (IV) bolus drugs constituted 68.8% with pantoprazole and ondansetron (85.4%) being the most frequent combination. CompatibilitySome drugs aren't compatible with each other or with IV solutions. From the IV medication syringe 2.5 mL was transferred into the 5-mL syringe containing 2.5 mL of lipid emulsion. High-Risk IV Medications Dosing Limits Guidelines of Care The purpose of this tool kit is to provide evidenced-based recommendations and best practices on setting and managing high-risk IV medications limit settings for adult patients in intensive and acute care units. All content is available on the global site. When both compatible and incompatible study results are available for the same drug pair. COMPATIBILITY OF DRUGS COMBINED IN A SYRINGE. 14th ed. In some cases, the manufacturer recommends administration of the undiluted drug. hXmo8+UEw'EUBJRmwNBRb8x0_N%p F9)c'R&(a&LH*$("A7(P&|I#\(NU?ANI"4R`2DVT@0AX|N4nE`] 4IV,\;{^Q8q9bcFO>C@Do\#+Uhju}4wQTLG/| {0pR(7%?$sM7kB(h9hY* ^?r37HE2hHGp0JE~fqpyzlFE'&abRoXIPoTD L ExUoib:"nt/x]q>=YZ+Bc#,%3}~(qYKjs@x' ? Call your doctor for medical advice about serious . The King Guide to Parenteral Admixtures is designed to help practitioners decide which alternative administration strategy is best. NPS MedicineWise disclaims all liability (including for negligence) for any loss, damage or injury resulting from reliance on or use of this information. %%EOF IV diazepam (valium) is incompatible with most drugs and fluids, including normal saline. Mixing is best avoided. What you should know about drug compatibility. Find the product you are looking for. The selected drug(s) and solution(s) will populate the Selected Items in the left pane. You can return to the Chart display by toggling back to Chart View. J Res Pharm Pract; (1): 37-40. Wolters Kluwer is a global provider of professional information, software solutions, and services for clinicians, nurses, accountants, lawyers, and tax, finance, audit, risk, compliance, and regulatory sectors. arrow_forward. The Vial2Bag Advanced 20mm admixture device is not compatible for use with all drug products. )sHQVzP` , For this reason, the decision to mix any two injection solutions whether in a syringe, in an infusion bag or at a Y-site should be based on a reliable reference. PEPIDs IV Compatibility Checker is available through any of our clinical decision support suites, allowing healthcare professionals to quickly check the compatibility of specific IV sites, drugs and solutions with their mobile devices oronline. Checklist: Top 25 software capabilities for planning, profitability and risk in the banking industry, Optimizing balance sheets and leveraging risk to improve financial performance, How the EU Foreign Subsidies Regulation affects companies operating in the single market, Understanding why companies have to register to do business in another state, Industry experts anticipate less legislation, more regulation for 2023. Select a second drug the same way, 3. hb```,Q ea8p3$H``h There are a number of drugs that are commonly delivered via syringe driver to patients having palliative care in the community (see box). List several factors that affect compatibility and stability of an intravenous solution. Special Sections on Stability and Storage The more medicines you take, the more difficult it can be to remember important information about them. Standards for Infusion Therapy. 3. New items will appear in the "Selected Items" field. Murney P. To mix or not to mix compatibilities of parenteral drug solutions. However, a small number of injection solutions are formulated in non-aqueous solvents to allow dissolution of a poorly water soluble substance in a small volume. Incompatibility can involve precipitation, ionic reactions, evolution of gas and denaturation of biological molecules. Other drugs which demonstrate solubility problems and which are formulated in injection vehicles other than simple aqueous solutions include digoxin, clonazepam, phenytoin, amiodarone and phytomenadione. It is a list of 33 antibiotics and their given stability in several different solutions. endstream endobj startxref Albumin ? Two observers performed visual evaluation independently immediately upon . Use the free Micromedex IV Compatibility app. For more products, please check the B. Braun Product Catalogue. However, the evolution of gas is a normal part of the reconstitution of some drugs, notably ceftazidime. We would be pleased to provide you with more information. Coverage of IV drug administration highlights dosage and IV administration instructions, including safety considerations and Y-site, syringe, and additive compatibilities. Compatibility of Selected IV Drugs (continued) Acyclovir Amikacin Amiodarone Ampicillin Ampicillin-sulbactam Anidulafungin Argatroban Azithromycin Aztreonam Bivalirudin Bumetanide Calcium gluconate Caspofungin Cefazolin Cefepime Cefotaxime Cefoxitin Ceftaroline Ceftazidime Ceftizoxime Ceftriaxone Ciprofloxacin Clindamycin Daptomycin Dexamethasone Dextrose 5% in water Diazepam Diltiazem . While published compatibility data exist for insulins and some of the blood products, most recently marketed biological drugs such as infliximab, interferons and recombinant coagulation factors have no such data available and mixing with other drugs is not recommended. 4: Color coding and drug separation to prevent drug incompatibilities through a clear indication of the drug. Micromedex IV Compatability is a reliable resource for on-the-go access to the industry's most trusted clinical reference information, providing users with more informed treatment decisions at the point of care. Two syringes taped together sounds like a recipe for disaster' date=' either for the patient or for the nurse - particularly with regard to increased risk for needle sticks. Practical information, tools and resources for health professionals and staff to help improve the quality of health care and safety for patients. PARENTERAL NUTRITION (PN) AND DRUG COMPATIBILITY The co-infusion of drugs and PN should be avoided. With this app you will have access to the largest, most comprehensive IV compatibility resource which: Includes drug-solution compatibility results as well as drug-drug compatibility results when creating an admixture or administering via Y-Site. This can include the rinsing of the infusion system with a neutral IV solution prior to the application of another drug. Step 1. These changes are consistent with new international guidelines for endocarditis prophylaxis, which have generally reduced the indications for using antibiotics. Drug Name Dose &/or Range Administration Compatibility Precautions Ketamine 1-2mg/kg Low dose for analgesia . Specialized in clinical effectiveness, learning, research and safety. In-line filters are able to retain solid particles of at least 0.2 m. Further publications showed that, depending on the ward type, up to 80% of IV drug doses were prepared with the wrong diluents.11. IBM Micromedex IV Compatibility (Mobile) IBM Micromedex Mobile IBM Micromedex Neofax (Mobile) IBM Micromedex Neofax and Pediatrics IBM Micromedex Pediatrics (Mobile) IBM Micromedex RED BOOK IBM Micromedex UltiMedex Clinical Knowledge Hours of Operation Micromedex Support is available 24/7. Anaesthesist; 52(5): 409-12, 10 Taxis K, Barber N. (2004) Incidence and severity of intravenous drug errors in a German hospital. To view all solution and drug compatibility results for a single drug, enter the IV Drug and Click "View Compatibility". The compatibility results are presented in a chart or list view, with the default chart view displaying all methods within the fields for the selected drugs and solutions. In this update we added a new monograph for TOCILIZUMAB. View the full Trissels monograph for more information on the physical and chemical characteristics of the drug. Micromedex IV Compatibility is a reliable resource for on-the-go access to the industry's . Dangerous incompatibilities can be prevented bya plausibility check regarding the SPC and available sources on compatibility information, also considering the material used for therapy (e.g. Eur J Clin Pharmacol; 59(11): 815-7, (2) Emami S, Hamishehkar H, Mahmoodpoor A, Mashayekhi S, Asgharian P. (2012) Errors of oral medication administration in a patient with enteral feeding tube. To remove an individual drug or solution, click on the X next to the name. To clear the items from the tool, click the Clear button. Incompatibilities of drugs in standard IV therapy can occur between: The unintended presence of precipitation and toxic products can cause various negative consequences for the patient. Many institutions and schools subscribe to Micromedex products, which translates into free access for you. ^P}M%@586:vaX-KF\6c:Zj;C8r8&}+MDU_M iVg 6qiv |fZ~d,NDF+ mTI\uPxuPh)":H"3&"Xz M9|AqouXOKX3ZuJ&!q\&`1 ,5 &l5@`,[%h6agz6SM0@ &cuu Includes routes, dosages, temperatures, and containers used to determine compatibility and stability. 2. You can either click on the X in the top right or press the Close button to return to the previous screen. Extensive TPN/TNA data. Critical Care Intravenous Drug Administration Guide For Use on ICU, HDU & CTCCU Page 1 of 44 April 2008 (For review April 2009) . Full information can be obtained from your pharmacy department Key References Adrenaline 18 1 Compatible (Reference 1) 1 "Handbook of Injectable Drugs" Lawrence Trissel available on www.medicinescomplete.com Empowering physicians with fast, accurate clinical answers, Beyond the call: How to differentiate your telehealth experience post-visit, Implementing 2023 updates to your Antimicrobial Stewardship Program. 20 years of helping Australians make better decisions about medicines, medical tests and other health technologies. Lexicomp Trissels IV Compatibility Databases. HK9D:E?FDg#{p*+ >^qnr YVNOBe/[\xwGj?LndXrn^-5 ,}c}ym)Ar&/(Z$$m{{}NYrT*#@-fI($y'[iRugP^2+ For example, some medications shouldn't be stored in PVC plastic containers. Learn more about our innovation hub and present your idea. Cs = Compatible Only if Drugs mixed in NS CD = Compatible Only if Drugs mixed in Dextrose C* =Conc./Time dependent, CALL PHARMACY dextrose IV soln. Title: 136192_NDH12 Author: BDTEMP1 Created Date: 1/14/2011 9:39:58 PM . Independent peer-reviewed journal providing critical commentary on drugs and therapeutics for health professionals, Provides health professionals with timely, independent and evidence-based information, Our new and ongoing programs for healthcare professionals. All drug components in the test samples were found to be chemically stable (less than 10% loss of intact drug) for at least 24 hours under the conditions being tested. All drug components in the test samples were found to be chemically stable (less than 10% loss of intact drug) for the entire period of the study under the conditions being tested, even if the study period was less than 24 hours. Fig. 574 0 obj <> endobj 610 0 obj <>/Encrypt 575 0 R/Filter/FlateDecode/ID[<7C5275BC3D5C496FB588ACDF9629EDDA>]/Index[574 66]/Info 573 0 R/Length 145/Prev 963922/Root 576 0 R/Size 640/Type/XRef/W[1 2 1]>>stream 0 This reference contains standard dilutions including IV admixture drug concentration, infusion volumes, and infusion rates. Eur J Clin Pharmacol; 59(11): 815-7, 11 Cousins, B Sabatier, D Begue, C Schmitt, and T Hoppe-Tichy. Select a drug or solution by clicking the Enter key on your keyboard or by using the Add button. Episode 51: Quit smoking. The King Guide is available everywhere, so we designed our subscriptions to be flexible. Keep a compatibility chart handy in your medication room or on your medication cart (in . A number of references, in addition to the manufacturer's product information, are available. dry mouth , chest pain or pressure, pain spreading to the jaw or shoulder , nausea, and. PflegenIntensiv; 2(1): 57, 13 Jack T, Boehne M, Brent BE, Hoy L, Kditz H, Wessel A, Sasse M. (2012)In-line filtration reduces severe complications and length of stay on pediatric intensive care unit: a prospective, randomized, controlled trial. Mixing solutions of parenteral drugs is generally not recommended because of the potential for incompatibility and consequent loss of activity of one or both drugs. A visual check for precipitation, turbidity or colour change should be carried out before administering the mixture, but does not guarantee compatibility. View answers to our most frequently asked question. 0 The problem is frequently observed when diazepam injection is diluted. Thyroid disease: challenges in primary care, To mix or not to mix compatibilities of parenteral drug solutions, difficulties with venous access limiting the number of intravenous lines available for continuous administration of multiple drugs, multiple drugs requiring parenteral administration within a short time frame such as in a home visit by a general practitioner. Making safe and wise decisions for biological disease-modifying antirheumatic drugs (bDMARDs) and other specialised medicines. This application provides the healthcare profession with a method of quickly checking the compatibility of any two of the following intravenous drugs at the Y-site: Acetylcysteine. Mixing solutions containing calcium or magnesium ions has a substantial risk of forming an insoluble calcium or magnesium salt. Over 600 IV drugs with at-a-glance view of compatibility in 12 fluids Over 3,200 primary source references Includes routes, dosages, temperatures, and containers used to determine compatibility and stability. Get in touch with us. You can also view different drugs and solutions that are compatible by clicking the drop-down arrows. Incompatibilities of drugs in standard IV therapy can occur between: drugs and inappropriate IV solutions as diluent two drugs (drug-drug incompatibility) when they are - mixed together, e.g. (2014) A clinical study on drug-related problems associated with intravenous drug administration. BMJ Qual Saf; 20(12): 1027-34, 6 Hpner JH, Schulte A, Thiessen J, Knuf M, Huth RG. Timely, independent, evidence-based information on new drugs and medical tests, and changes to the PBS and MBS. This was the third project that I was assigned at Oconee Medical center. Premium IV-Administration Set with AirStop andPrimestop, Antimicrobial modified four-lumen catheter sets for catheterization of the vena cava according to the Seldinger method with the possibility of ECG based Central Venous Catheter tip placement and position control, 0.2 m infusion filter with positively charged membrane, Stopcock system for infusion therapy and monitoring. These include the Australian Injectable Drugs Handbook.2 Table 1 shows some of the compatibility and incompatibility data currently available. Download INTRAVENOUS COMPATIBILITY CHART - Drug Information For The . Sodium bicarbonate and mannitol solutions should not be used as diluent for intravenous drug administration. Download the free Micromedex IV Compatibility app from iTunes or Google Play. Separating the drug doses by time and place. Incorporation services for entrepreneurs. The most prominent example of a pH-related reduction in solubility is dilution of phenytoin sodium injection. Copyright 1993-2021 Serving legal professionals in law firms, General Counsel offices and corporate legal departments with data-driven decision-making tools. !k> Consequences of physicochemical drug incompatibilities are particularly severe in neonate and pediatric patients.1,4,6, There is little published scientific information about the frequency of drug incompatibility reactions. J Res Pharm Pract; (1): 37-40, 4 Vijayakumar A, Sharon EV, Teena J, Nobil S, Nazeer I. Each monograph contains stability data, administration guidelines, and methods of preparation. An internet connection is not required, allowing you to make decisions with confidence at anytime, from anywhere. Purpose/objectives: To examine the cause(s) and types of IV incompatibilities that can occur in the oncology population, to present information on commonly used oncologic medications, to identify resources available to nurses, and to provide specific interventions designed to prevent incompatibilities in various oncology settings. i\ M, u=UZ"UiCjJ; &0tOQsy pj/N&]W&/iqh&hIiM7DwZYm- j{jA[;N`9T`xk`U MM>)y@ofS5Nk5zv|\\)y9 ?;~20CLw}tb,G"5nDWyQ(EKQ}L%IzoJO*@z. This review focused on analyzing the physical and chemical compatibility of the IV drugs most commonly used through Y-site infusion in the ICU setting and summarizing the information obtained in a double-entry chart. The IV drug compatibility chart is based on information from the, ThisIVDrugCompatibilityChartisprovidedasaquickr, itisadvisedthatyoucheckwithapharmacistforr. Some cannot be safely diluted in infusion bags. Definitions for the following types of compatibility testing are as follows: The compatibility information presented is based on one of four (4) ratings: In the chart display, find detailed information about a specific pair of drugs and administration route by clicking on the compatibility type link within the table. http://www.ncbi.nlm.nih.gov/pubmed/17937330, drugs and inappropriate IV solutions as diluent, two drugs (drug-drug incompatibility) when they are, drugs and adjuvants (preservative, buffer, stabilizer, solvent). From a single drug to multiple drugs is shown in a clear easy to read format. Procedure Details adsorption). Iran J Pharm Res; 14(suppl); 87-93. B. Braun ensures high security standards throughout the product life cycle by using globally accepted standards. A recent warning has been issued about mixing calcium-containing solutions, including Hartmann's solution, with ceftriaxone causing the formation of the insoluble ceftriaxone calcium salt.1. Do Not Copy, Distribute or otherwise Disseminate without express permission. @z0012c`,' Handbook of Injectable Drugs, 16th Edition, Enoxaparin Sodium Solution for Injection, Manufacturer's Standard, Rivaroxaban Versus Enoxaparin for Thromboprophylaxis After Hip, Anticoagulation Dosing Guideline for Adult COVID-19 Patients, Estonian Statistics on Medicines 2016 1/41, Protective Effect of Diclofenac and Enoxaparin in L- Asparaginase Induced Acute Pancreatitis in Rats, Low-Molecular-Weight Heparins in the Treatment of Acute Coronary Syndromes, Estonian Statistics on Medicines 2013 1/44, Addition of Low Molecular Weight Heparin to Antiplatelet in Patients, Reinvestigation of Synthesis of Enoxaparin Under PTC Conditions, Generic Name Brand Name Dose Form 0.5 Normal Saline Sodium Chloride Iv Soln, Acetylsalicylic Acid Compared with Enoxaparin for the Prevention of Thrombosis and Mechanical Ventilation in COVID19 Patients: a Retrospective Cohort Study, Australian Public Assessment Report for Enoxaparin Sodium, Venous Thromboembolism, Coagulation and Cancer Van Doormaal, F.F, Thromboprophylactic Treatment with Rivaroxaban Or Dabigatran Compared with Enoxaparin Or Dalteparin in Patients Undergoing Elective Hip- Or Knee Replacement Surgery, Attachment: Extract from Clinical Evaluation: Nadroparin, Enoxaparin Sodium Injection I.P. Midazolam (Versed) YES Midazolam (Versed) YES Midazolam (Versed) ** View Text Version Copyright Report All rights reserved. To determine the physical intravenous Y-site compatibility of 19 commonly used medications at pediatric concentrations with 3 different types o . %PDF-1.5 % Each monograph reports the routes, dosages, temperatures, and containers used to determine compatibility and stability from fully referenced peer-reviewed primary sources.