The drug was FDA-approved more than 65 years ago. By Steve Kirsch in fluvoxamine Feb 14, 2021 The case for fluvoxamine for treating COVID-19 A very short op-ed arguing for using fluvoxamine against COVID. . In September, he resigned as CEO and gave up his board seat. Jeffrey Glenn, an infectious disease professor at Stanford University, calls the inaction on the current evidence on the table "criminal.". If you start 5 days after symptoms, all bets are off. I will . Also, this drug is only prescribed by psychiatrists so most doctors have no experience whatsoever with the drug. On January 22, 2021, thirty key opinion leaders (KOL) from NIH, CDC, and leading academic institutions met to review the evidence for using fluvoxamine for treating COVID. Here are my answers. Its whether Merck can make a killing that matters. Medicine today isnt about saving your life. Yeah, its possible, he told mehe also says that he has regularly seen Kirsch manipulate evidence so that it seems to support claims that are, in reality, baseless. There are 4 outpatient studies that have been done (2 at WashU (see. Some countries dont have fluvoxamine so this is the alternative. While Fauci was crafting national pandemic policies, Fauci's wife [Christine Grady, Chief Bioethicist, NIH] was back stopping [them]." Report coming soon. Fluvoxamine has a 40 year safety track record. He might be a good snake oil salesman., I experienced this myself when, on one call, we discussed several studies. That covers almost 150,000 of them, which happened before vaccinations began. Eventually, a press representative who was listening in, David Satterfield, unmuted his microphone to suggest we finish our conversation by email. My crime? Hes refused to accept the results of a hydroxychloroquine trial that showed the drug had no value in treating covid, for instance, instead blaming investigators for poor study design and statistical errors. Its motivated out of his sense of keeping people safe and advancing health care.. At the beginning of the COVID-19 pandemic, Steve Kirsch created the COVID-19 Early Treatment Fund (CETF) to finance trials of off-patent drugs in an attempt to find a potent treatment that had been staring us in the face. Waiting months for the phase 3 trial to complete is nuts. It is currently approved for treatment of depression and obsessive compulsive disorder (OCD). The data we have today with just 2 clinical trials (RCT and confirmatory RWE) is compelling. 90,000 Americans will die from COVID in just the next 3 weeks, a third of recovered patients from COVID will return to the hospital within 5 months and 1 in 8 die, Lenze fluvoxamine RCT that was published in JAMA. The medical community doesnt care about saving lives. I bumped up the reward to $1M. So you can address your OCD and if you get COVID, youll can up the dose. These people never called the researchers whose trials they claimed showed no effect. Some people are jittery, but usually that is because the doctor either prescribed a dosage higher than 50mg twice a day or didnt notify the patient to. Hes also publicly railed against what he claims is a campaign against drugs like fluvoxamine and ivermectin. It is not unusual to be wary of developing science, or wrong to be skeptical of pharmaceutical companies. Kirsch is a serial entrepreneur who has spent decades pitching the next big thing, whether optical mice (Mouse Systems), document processing (FrameMaker), search engines (Infoseek), digital. After several failed attempts to stop the progression of his disease, he designed his own protocol for chemotherapy and doctor-shopped to find an oncologist who would give it to him. 4000fluvoxamine750 The combined p value of the two studies is <.0001. . Or just depression about the vaccine mandates? Fluvoxamine is a selective serotonin reuptake inhibitor (SSRI), a class of anti-depressants, mostly prescribed for people suffering from an obsessive-compulsive disorder. Added to FLCCC protocols and Fareed-Tyson protocol among others. That way you can start immediately. just like ivermectin). Fluvoxamine is used commonly to treat obsessive-compulsive disorder (OCD), social anxiety disorder and depression. Here is what, e) which concluded: Under a variety of assumptions, fluvoxamine shows a high probability of preventing hospitalization in outpatients with COVID-19., For more about fluvoxamine (and other SSRIs that work), see, fluvoxamine completed a Phase 3 study showing it works that was published in the Lancet Global Health, NIH basically dismissed the fluvoxamine study as I predicted they would, few people werent afraid of expressing their displeasure, the highly acclaimed Bangladesh mask study showed, Johns Hopkins has incorporated fluvoxamine in their treatment guidelines, Ontario has become the first province to list fluvoxamine as a treatment doctors can consider for patients. Since making a fortune as the founder of Infoseek, an early search engine that was the Google of its day, Kirsch has spent tens of millions of dollars fighting humanitys biggest threats. Substitutions. A video presentation by Steve Kirsch, Executive Director of the Covid-19 Early Treatment Fund. Enter the email address you signed up with and we'll email you a reset link. Why the FDA should grant an EUA for fluvoxamine immediately, Links to evidence about fluvoxamine including the public data repository, Here's the first one: Ive talked to doctors who are extremely familiar with the drug and all the trial results and they would prescribe it to their patients. Steve Kirsch's Newsletter ^ | 02/26/22 | Steve Kirsch. The Lancet paper showed that if you were treated early enough and took the drug as prescribed (it only works if you take it), it was shown to reduce your chance of death by 12X making it far more effective than any other drug for COVID. Steve Kirsch is a Silicon Valley philanthropist. He considers himself an expert in something that he doesnt have training or experience in, and hes not following scientific methods to assess data.. 95% confidence effect size is 75% or more. Both of them encouraged anyone reading this article to get vaccinated. Today, we are letting people drown and we are not even telling them there is a life preserver they can ask for today with compelling evidence that is under consideration by the life preserver safety group. Fluvoxamine, COVID, pandemic, . Fluvoxamine is the poster child of the COVID-19 Early Treatment Fund (CETF). People are dying because of physician fear of a new treatment with a 100% success rate and a solid mechanism of action. Nov 12: Steve Kirsch gives talk on CETF to HarvardBusiness School hosted by Dr. Seftel Nov 13:Mass COVID outbreak at GGF is now publiclyknown Nov 16: Seftel, the track physician at GGF, startsFLV . Were having trouble saving your preferences. Its board told him that if he wanted to remain part of the company he would have to stop making public anti-vaccine statements. About 10 minutes on the internet will show you those two gentlemen, who have appeared together, have been extensively fact checked for false or misleading claims or misuse of VAERS reporting and other data. Author Affiliations . He is frequently brash and interruptive, peppering dire warnings about vaccines with veiled aspersions toward Anthony Fauci and vague references to influential people who agree with him in private but cannot speak publicly. If you cant lay off the java, then try fluoxetine (Prozac). BOMBSHELL: Top biostats professor admits we have NO CLUE # of people KILLED by COVID vaccines, he wrote. But they dont want their names used. P-value was 10^-14 on that study (done by Dr. ICER: After two weeks (since it was a tight knit community, everyone could see what was happening to the two groups), every track worker who got sick with COVID, demanded the drug. Every earlier study of fluvoxamine (such as observational studies) showed it work and the mechanism had been shown. Its really, really common for a small effect, something that looks exciting, to be a statistical fluke when you look at a larger population. Entrepreneur Steve Kirsch who holds an early patent for the optical mouse decided to get involved in treating Covid. I couldn't agree more. These huge businesses do often prioritize profits over human health: in 2009, Pfizer paid a $2.3 billion settlement over kickbacks and fraudulent marketing, including a $1.3 billion felony fine. I agreed to do it partially because I respect Bob [Siliciano] so much, and partially because I thought the concept was excellent, said former board member Doug Richman, a prominent HIV drug researcher at the University of California San Diego and former member of the funds scientific advisory board. sorry about that. Vitamin D, NAC, betadine, aspirin, and Nigella sativa are all super cheap, effective, and available without a prescription. This looks ominous, but it harmless. The NIH wrote a bullshit rejection because the FDA told them not to approve it. Today, if we follow the CDC advice, nearly 100,000 people a month will die from COVID. Dr. Eric Lenze: So the results were really pretty. After I ended the Zoom meeting, Satterfield called me to apologize for cutting us off. People are dying. The agency quickly slapped down the comments from Kirsch, a tech mogul with a fortune once estimated at $230 million, even as the claims triggered a flurry of false social-media posts attributing. It is about following orders and making money for the drug companies and protecting the doctor from liability and losing his medical license. Fluoxetine is just as effective. They were all given the drug soon after symptoms and the placebo group was pure in that they were not taking any COVID drugs. Fluvoxamine public data repository - Google Drive, On Cytokines, Fluvoxamine and COVID-19 Part 1, Jon-Emile S. Kenny MD[@heart_lung] You see, we have a kind of allergy to the past; its our national disease, and the very assurance with which you insist that the past is within the present is l, On Cytokines, Fluvoxamine and COVID-19 Part 2, Jon-Emile S. Kenny MD[@heart_lung] Apocalypse is played out now on a personal scale; it is not in the sky above us, but in our bed. -Mark Doty Introduction With a proposed pathway coupling patho, Effect of Fluvoxamine vs Placebo on Clinical Deterioration in Outpatients With Symptomatic COVID-19, This randomized trial compares the effects of fluvoxamine, a selective serotonin reuptake inhibitor with immunomodulatory effects vs placebo on a composite of dyspnea or pneumonia and oxygen desaturation among adult outpatients with polymerase chain reactionconfirmed mild coronavirus disease 2019 (, Prospective cohort of fluvoxamine for early treatment of COVID-19, Abstract. The drugs mechanisms of action were explained to the KOL panel which voted 2>1 in favor of fluvoxamine. 22, 2021, 9:00 a.m. Steve Kirsch , a former tech entrepreneur who earned a fortune worth up to $300 million, has been showcased on TrialSite a few times for his activity supporting the clinical development of repurposed drugs for COVID-19 treatments. Some people report mild nausea while on the drug (stops when stop the drug). The. The results would, eventually, set Kirsch on a collision course with the scientific establishment. The paramedics will think you are on drugs. This advice is now outdated. For decades, coders wrote critical systems in C and C++. Fluoxetine is just as effective. . He may not be a good scientist, but hes smart, says WVUs Feinberg. As of November 13, fluvoxamine has been proven to work in every trial that has published results, including outpatient and inpatient studies. The medical community doesnt care about saving lives. Thats pretty typical, but your mileage may vary. After boosting unproven covid drugs and campaigning against vaccines, Steve Kirsch was abandoned by his team of scientific advisersand left out of a job. Note that some of these articles are inaccurate. This is why Cliff doesnt talk to me. Read More fluvoxamine The Fluvoxamine FAQ Refresh. Doctors who have used fluvoxamine in the US and other countries swear by it. Please read and agree to the disclaimer before watching this video.. Steve Kirsch On COVID Early Treatment and CensorshipSteve Kirsch is an entrepreneur and . The US government accused Janssen of improperly promoting the antipsychotic drug Risperdal to dementia patients despite the drug increasing deaths in the elderly. More recently, hes adopted extremist positions on covid vaccines, which he alleges are toxic. He has claimed that one in 1,000 people who have received mRNA vaccines have died as a result, and even claimed the vaccines kill more people than they save at an FDA public forum, which was first reported by the Daily Beast. My experience is very typical. . How I recommend people treat COVID and the fascinating backstory of how fluvoxamine was discovered. It's hard to ignore this lecture in explaining why the drug is so effective. Its whether Merck can make a killing that matters. Food/drugs to avoid while on fluvoxamine. In the early days of the pandemic, as billions of dollars poured into the hunt for novel treatments and vaccines, veteran Silicon Valley entrepreneur Steve Kirsch did what hes always done: He went looking for an underdog. Fluvoxamine has at least a 30% hospitalization and death benefit. FDA official fluvoxamine rejection. I didnt intend to spend a lot of time on Steve in particular, but that video was so influential.. We have a bounty of vaccines and more on the way, but drugs that treat the disease are vital too if we want to keep people alive and bring the pandemic under control. Decreasing the dosage or stopping the medication will mitigate symptoms within hours. All can merit a fluvoxamine prescription based on traditional diagnoses. I also think it makes a lot of sense to look for pre-existing drugs that can help treat covid symptoms. . Get your prescription in advance of getting COVID. Steve Kirsch is a high-tech serial entrepreneur based in Silicon Valley. If you take fluvoxamine, please avoid caffeine while on the drug. In two trials (both published studies in peer reviewed journals with Editor's Choice in both cases), the drug had a 100% effect size in protecting against hospitalization from the respiratory symptoms from COVID. Added to FLCCC protocols and Fareed-Tyson protocol among others. . Drug researchers at Washington University in St. Louis reached out to Kirsch looking for $67,000 to finish a very smallbut placebo-controlledtrial. Keeping this drug off the NIH Guidelines does nothing to reduce the death rate. Fluvoxamine at 50mg twice a day for 14 days is a very well-tolerated drug (as long as you avoid caffeine and alcohol) for the treatment of COVID infections. Fluvoxamine has a systematic review and meta-analysis published in a top medical journal. It was recommended back in January 2021 by a key opinion leader (KOL) panel to be used, but it took a year for, because they were rejected by 10 journals. We could have saved a lot of lives. Steve wanted to say, Look, Ive got all these famous [infectious disease] docs and researchers, and they all say give fluvoxamine a chance, Judith Feinberg, one of the former CETF advisory board members and vice chair of research at the West Virginia University School of Medicine, told me. You can experience serious side effects if you do not pay attention to interactions such as if you are currently on another SSRI of a different type. David Boulware, a researcher at the University of Minnesota, received $125,000 to test the drug against covid. There were no studies reported out so far where fluvoxamine made things worse or neutral. NIH doesnt want you to get the drug since it would compete with Molnupiravir, so fluvoxamine will never make the NIH guidelines. Since then, he has continued to promote fluvoxamine, along with ivermectin and hydroxychloroquine. Why fluvoxamine isnt used. Three of the four outpatient trials have been reported out: all were successful. No long haul symptoms if you start the drug ASAP after first symptoms. Please. Hes probably the closest thing Kirsch has to a nemesis, regularly disputing his assertions in blog posts and private email exchanges with Kirsch and his friends. Ivermectin and fluvoxamine have been confirmed in Phase 3 trials. To vet proposals, he recruited a powerhouse advisory board of prominent biologists, drug developers, and clinical researchers, led by world-renowned drug researcher Robert Siliciano of Johns Hopkins. Kirsch said that his attempts to promote fluvoxamine are being curtailed. saying that the per-protocol analysis was arbitrary and other excuses. When I asked him why so many experts in the field disagreed with him, he alleged there were effortseither malicious or negligentto suppress evidence of cheap, effective covid treatments. The paramedics will think you are on drugs. It could do nothing. Zero. At that dose, no side effects were reported for his patients (I know of only one person who had mild nausea at that dose) and everyone reversed out their symptoms in an average of 3 days. Flavio Cadegiani and Steve Kirsch's studies didn't make the cut. upcoming events, and more. The medical community did nothing (with a few exceptions like Dr. Seftel). Kirsch: Yes, but you could easily watch that 60 Minutes story and believe that we need more data before people should start using fluvoxamine. Long haul. Steve Kirsch: Vaccine Killing Millions, Treatments, VAERS, 5-Month Death Signal, Mystery Clots Embed 1.15K 'This Has Cost Millions of Lives': Steve Kirsch on Suppression of Repurposed Drugs and a Spike in Deaths 5 Months After Vaccine Rollout American Thought Leaders AMERICAN THOUGHT LEADERS JAN JEKIELEK Show more Loading comments. Part of TV News Archive. In June, after CETFs advisory board resigned, Kirsch did a Facebook Live video with Zelenko and celebrity rehab coach Dr. Drew. So why would we wait when lives are being lost? The anecdotal data of 100% success rates is further icing on the cake. Hes also recently increased the number of Americans he claim have been killed by the vaccine from 25,0000, to 150,000, or even as many as 250,000 Americans. In short, a lot of mumbo jumbo. Consider masks by contrast. The NIH Guidelines committee is being very slow to react (we have no idea if they are even considering the drug because nobody is allowed to know that because all their deliberations are kept secret). He is very smart, and knows that he is very smart, and sometimes he behaves like he thinks he's the smartest guy in the room, whether he is or isn't., Kirschs response was to take his name off articles hed written about vaccine deaths, changing the authorship to VaccineTruth., On July 1, he tweeted from his personal account, My publicly shared concerns regarding the safety of the COVID-19 vaccines may have had a negative impact on my company, M10. Our in-depth reporting reveals whats going on now to prepare you for whats coming next.